Yuan GAO ^a,b,c, Fei WANG ^a,b, Dong-Sheng ZHOU ^b, Yan LI ^a, and Ji-Kai LIU ^a,*

^a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

^b BioBioPha Co., Ltd., Kunming 650201, China

^c Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Received 11 October 2011; Accepted 23 November 2011

© The Author(s) 2011. This article is published with open access at Springerlink.com

Abstract

One rare tetracyclic macroline-type indole alkaloid, named rauvoyunine A (1), and two new picraline-type alkaloids rauvoyunines B and C (2 and 3) were isolated from the aerial parts of Rauvolfia yunnanensis. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 2 and 3 were evaluated for their in vitro cytotoxicity against five human tumor cell lines.

文章链接：https://link.springer.xilesou.top/article/10.1007/s13659-011-0023-7